Ligand-gated ion channels transduce electrochemical signals in neurons and other excitable cells.Aside from canonical ligands, phospholipids are thought to bind specifically to the transmembrane domain of several ion channels.However, structural details of such lipid contacts remain elusive, partly due to limited resolution of these regions in expe
Integrating augmented reality technology in education: vector personal computer augmented reality [version 2; peer review: 2 approved, 1 approved with reservations]
Background: Educators often face difficulties in explaining abstract concepts such as vectors.During the ongoing coronavirus disease 2019 (COVID-19) pandemic, fully online classes have also caused additional challenges to using conventional teaching methods.To explain a vector concept of more than 2 dimensions, visualization becomes a problem.Altho
Efficacy and Tolerability of Two Quadruple Regimens: Bismuth, Omeprazole, Metronidazole with Amoxicillin or Tetracycline as First-Line Treatment for Eradication of Helicobacter Pylori in Patients with Duodenal Ulcer: A Randomized Clinical Trial.
AimTo evaluate the efficacy and tolerability of tetracycline vs.high-dose amoxicillin in bismuth-based quadruple therapy for Helicobacter pylori(H.pylori) eradication.MethodsThis randomized, open-label clinical trial included 228 patients with H.pylori infection and duodenal ulcer without a history of H.pylori treatment.Patients were randomly divid
Fatigue reliability of welded joints accounting for uncertainties in weld geometry
Fatigue reliability assessment of welded joints can consider the uncertainties from various sources and can establish the design criteria and inspection plans.The present paper aims to address the uncertainties explicitly.The notch strain approach that accounts for the effects of Guggul the misalignment, local notch, and crack-like imperfection, wh